Observation of Kawasaki disease-related indexes and the study of relationship between myocardial enzyme changes and coronary artery lesions

L. Niu, X.-J. An, M.-Y. Fu, X.-H. He, Q.-W. Wang

Department of Cardiovascularology, Xuzhou Children’s Hospital, Xuzhou, Jiangsu, P.R. China. anxinjiang78@126.com

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• Cardiology

OBJECTIVE: To discuss the significance of Kawasaki disease-related laboratory indicators and relationship between myocardial enzyme changes and myocardial enzyme changes in children with Kawasaki disease.

PATIENTS AND METHODS: Make an observation of C-reactive proteins and immune globulin changes in children with Kawasaki disease, and also a comparison about the myocardial enzyme changes between the children with myocardial enzyme changes and others without lesions.

RESULTS: Compare the study group before treatment with the control group of normal children, there are significant differences in the levels of CRP, IgG, and IgM, and the difference was statistically significant (p < 0.05); make a comparison about the levels of AST, LDH, CK, HB-DH, and CK-MB in the group with or without coronary artery lesions, the difference was not statistically significant (p > 0.05).

CONCLUSIONS: Relevant laboratory indices play an important role in the early diagnosis of Kawasaki disease. Myocardial injury and coronary artery lesions in children with Kawasaki disease have no correlation between each other, and there has an inconsistency characteristic.

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