Association of invasive breast carcinoma and multicentric high grade astrocytoma: a Case Report with a review

P. Hossein pour, M. Forouzandeh §, A. Naderi Beni #, Z. Naderi Beni, P. Hoseinpour*

Department of Pathology, § Department of Radiology, and # Department of Ophthalmology; Shahrekord University of Medical Sciences and Health Services, Shahrekord, Iran *Biotechnology, Jawaharlal Nehru Technological University, Hyderabad (India)

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• Oncology

Breast cancer is the most common cancer in women. Multicentric gliomas are uncommon lesions of the central nervous system (CNS) with an unprecise rate of occurrence that diffusely infiltrate large portions of the brain. High grade astrocytoma is the most agressive form of gliomas and often has a distinct neuroimaging pattern with a poor prognosis.
We report a case of a 29-year-old woman with primary breast carcinoma and high grade astrocytoma subsequently developed.
The woman was treated by mastectomy and 20 months later she exhibited a transient facial paralysis. Magnetic resonance imaging (MRI) revealed two cranial masses suspicious of metastasis. A complete tumor removal from the brain was performed. On histological examination, this tumor was a high grade astrocytoma.

Corresponding Author: Afsaneh Naderi Beni, MD; e-mail: a_naderibeni@yahoo.com

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