The risk of pulmonary complication after surgery for gallstone disease

Shan-Ping Jiang, Li-Wen Huang, Yi-Li Zhao, Jun Min*, Jie Wang*

Department of Respiratory Medicine, the Second Affiliated Hospital, Sun Yat-Sen University, GuangZhou, China *Department of Hepatobiliary Surgery, the Second Affiliated Hospital, Sun Yat-Sen University, GuangZhou, China

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• Respiratory Medicine

Objectives: To identify the risk factors of postoperative pulmonary complications (PPC) after surgery for gallstone disease.

Methods: A total of 544 patients undergoing open surgery for gallstone disease were retrospectively studied. Univariate and multivariate logistic regression were used to analyze each factor.

Results: There were 24 factors relating to PPC in univariate logistic analysis. And multivariate logistic analysis identified 5 independent risk factors associated with PPC, including perioperative aerosol therapy (OR = 5.906), duration of postoperative antacids therapy (OR = 1.145), duration of operation (OR = 1.011), preoperative serum albumin (OR = 0.689), postoperative analgesia (OR = 0.059), Logistic regression equation for predicting the risk of PPC was P(1) = 1/[1 + e-(- 9.803 + 1.776 x A + 0.135 x B + 0.011 x C – 0.372 x D – 2.835 x E)].

Conclusion: Perioperative aerosol therapy, duration of postoperative antacids therapy, duration of operation, preoperative serum albumin and postoperative analgesia were independent risk factors associated with PPC in patients undergoing surgery for gallstone disease.

Corresponding Author: Shan-Ping Jiang, MD; e-mail: jiangsp@mail.china.com

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