Magnesium levels and mortality relationship in patients with Acinetobacter baumannii detected in the Intensive Care Unit

M. Doganci, G.E. Doganay

Gulhane Faculty of Medicine, Health Sciences University, Ankara Atatürk Sanatorium Training and Research Hospital, Anesthesiology and Reanimation Clinic, Ankara, Turkey. melekdidik@hotmail.com

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• Intensive Care

OBJECTIVE: Acinetobacter baumannii (A. baumannii) causes serious nosocomial infections, especially in Intensive Care Units (ICU). Studies have shown that magnesium (Mg) levels change in sepsis. This study aimed to investigate the effect of Mg levels on mortality in patients with A. baumannii sepsis in the ICU.

PATIENTS AND METHODS: 140 patients who were hospitalized in the tertiary ICU between January 2018 and March 2020 and who were found to have A. baumannii sepsis in their culture follow-ups were included in the study. Demographic information of the patients, Mg levels during hospitalization and follow-up, and various data in the ICU were recorded.

RESULTS: The factors that predicted one-month mortality were old age, APACHE II score, CCIS, A. baumannii detection in the early stages of ICU admission, and high Mg level on day A. baumannii was detected, and the lowest Mg level after A. baumannii was detected in the early period. According to the multivariate logistic regression analysis, age increase [OR (95% CI): 1.062 (1.009-1.117)], APACHE II increase [OR (95% CI): 1.251 (1.141-1.372)], and early detection of A. baumannii during ICU admission [OR (95% CI): 0.902 (0.845-0.962)] were found to be factors that increase one-month mortality.

CONCLUSIONS: Hypermagnesemia in patients with A. baumannii indicates longer-term mortality, while a rapid decrease in Mg levels is a predictor of early mortality. Keeping Mg levels of patients within the reference range with frequent Mg measurement reduces mortality. Knowing colonized patients during admission to the ICU may be useful as an indicator of A. baumannii infection development and mortality risk.

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