Vitamin D supplementation during pregnancy inhibits the activation of fetal membrane NF-κB pathway

OBJECTIVE: Nuclear Factor-κB (NF-κB) is an important member of the basic cellular inflammatory pathway that regulates inflammation and apoptosis in fetal membranes. Vitamin D (VD) exerts its anti-inflammatory and immunomodulatory effects via the NF-κB pathway. This study was designed to investigate amniotic fluid NF-κB levels in pregnant women undergoing VD replacement therapy. PATIENTS AND METHODS: … Continue reading Vitamin D supplementation during pregnancy inhibits the activation of fetal membrane NF-κB pathway