Eur Rev Med Pharmacol Sci 1999; 3 (5): 205-209

Neurological involvement in antiphospholipid antibodies syndrome (APS)

A. Amoroso, A.P. Mitterhofer, G.M. Ferri, S. Galluzzo, M. Vadacca, A. Afeltra

Department of Medicina Clinica, “La Sapienza” University – Rome (Italy)


Antiphospholipid antibodies (aPL) have been most strongly associated with a syndrome (APS) characterized by venous and/or arterial thrombosis, thrombocytopenia, recurrent fetal losses and a variety of non-thrombotic and thrombotic neurological disorders. Cerebral ischemia associated with aPL is the most common arterial thrombotic manifestation. Other neurological syndromes, such as cognitive dysfunction, dementia, psychosis, depression, seizures, chorea and transverse mielopathy, have all been associated with antiphospholipid antibodies.

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To cite this article

A. Amoroso, A.P. Mitterhofer, G.M. Ferri, S. Galluzzo, M. Vadacca, A. Afeltra
Neurological involvement in antiphospholipid antibodies syndrome (APS)

Eur Rev Med Pharmacol Sci
Year: 1999
Vol. 3 - N. 5
Pages: 205-209