Eur Rev Med Pharmacol Sci 2000; 4 (1): 21-24

Double-blind, randomized clinical trial of troxerutin-carbazochrome in patients with hemorrhoids

F. Squadrito, D. Altavilla, S. Oliaro Bosso*

Istituto di Farmacologia, Servizio di Farmacologia Clinica, Università degli Studi di Messina (Italy)
*Pharmafar Srl – Torino, Italy

Abstract. – This multicenter, double-blind, randomised study was undertaken to determine the efficacy and safety of a combination of troxerutin 150 mg and carbazochrome 1.5 mg compared to carbazochrome alone in patients with acute uncomplicated hemorrhoids. Patients were administered by the intramuscular route (one ampoule) twice daily for one week. Both subjective and objective efficacy variables significantly improved in the combination drug group only, thus demonstrating the rationale for a combination therapy. Treatments were safe and well tolerated either at a local or systemic level.

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To cite this article

F. Squadrito, D. Altavilla, S. Oliaro Bosso*
Double-blind, randomized clinical trial of troxerutin-carbazochrome in patients with hemorrhoids

Eur Rev Med Pharmacol Sci
Year: 2000
Vol. 4 - N. 1
Pages: 21-24

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