MiR-203 regulates proliferation and apoptosis of ovarian cancer cells by targeting SOCS3

OBJECTIVE: Cytokine signal transduction inhibitor 3 (SOCS3) negatively regulates Janus kinases (JAK) – signal transducer and activator of transcription (STAT) pathway. Bioinformatics analysis revealed a targeted relationship between miR-203 and SOCS3 mRNA. This study investigated the role of miR-203 in ovarian cancer cell proliferation and apoptosis. PATIENTS AND METHODS: Ovarian cancer tissues and adjacent tissues … Continue reading MiR-203 regulates proliferation and apoptosis of ovarian cancer cells by targeting SOCS3