OBJECTIVE: The incidence of chronic pain increases with age and comorbidities, a particularly relevant issue in the elderly over the age of 80 years. Thus, the choice of the best analgesic treatment is difficult to make. The therapeutic priority in elderly patients is to favor the least invasive route of administration, and the minimum effective … Continue reading Efficacy and tolerability of tapentadol prolonged release in the elderly and fragile patient: an observational study