MicroRNA-28-5p regulates glioma cell proliferation, invasion and migration by targeting SphK1

OBJECTIVE: MicroRNAs (miRNAs) are a conserved class of endogenous and short non-coding RNAs that post-transcriptionally regulate the expression of genes involved in diverse cellular processes. MiR-28-5p has been reported to be associated with several cancers, including human glioma. However, the roles of miR-28-5p in glioma development are poorly understood. MATERIALS AND METHODS: Sixteen human glioma … Continue reading MicroRNA-28-5p regulates glioma cell proliferation, invasion and migration by targeting SphK1