MiR-129 reduces CDDP resistance in gastric cancer cells by inhibiting MAPK3

OBJECTIVE: Abnormal expression of mitogen-activated protein kinase 3 (MAPK3) is related to invasion, metastasis, and drug resistance of multiple tumor cells. MiR-129 expression is associated with gastric cancer. Bioinformatics analysis showed a targeting relation between miR-129 and MAPK3. This study investigated whether miR-129 plays a role in regulating MAPK3 expression, affecting proliferation, apoptosis, and cisplatin … Continue reading MiR-129 reduces CDDP resistance in gastric cancer cells by inhibiting MAPK3