OBJECTIVE: This study aims to investigate the role of Chi3l1 in Acetaminophen (APAP)-induced liver injury. MATERIALS AND METHODS: In vivo model of liver injury was established in mice administrated with APAP (250 mg/kg) or equivalent phosphate-buffered saline (PBS). Mouse liver tissues were collected at 1 h, 3 h, 6 h, 12 h, and 24 h … Continue reading Chi3l1 regulates APAP-induced liver injury by promoting macrophage infiltration