OBJECTIVE: Skin cancer severely threatens the public health. Dual-specificity protein phosphatase 22 (DUSP22) characterizes with multiple roles regulating cell growth, proliferation and gaining. This study aims to investigate the regulatory role of DUSP22 on aging of skin cancer cells and clarify molecular mechanisms, along with potential application value. PATIENTS AND METHODS: HS-1 skin cancer cells … Continue reading DUSP22 promotes senescence of HS-1 skin cancer cells through triggering MAPK signaling pathway