OBJECTIVE: Glycogen synthase kinase-3β (GSK-3β) can negatively regulate Wnt/β-catenin signaling pathway via degrading β-catenin protein, and plays suppressing roles in various tumors. Its role in bladder cancer pathogenesis is still unclear. In bladder cancer tissues, expression of microRNA-9 (miR-9) is significantly elevated. This study investigated the effect of miR-9 in modulating GSK-3β expression, Wnt/β-catenin pathway … Continue reading Target inhibition on GSK-3β by miR-9 to modulate proliferation and apoptosis of bladder cancer cells