Regenerative surgery performed with Platelet-Rich Plasma used in sinus lift elevation before dental implant surgery: an useful aid in healing and regeneration of bone tissue

F. Inchingolo 1,3, M. Tatullo 3,4,5, M. Marrelli 3,5, A.M. Inchingolo 6, A.D. Inchingolo 7, G. Dipalma 3, P. Flace 4, F. Girolamo 4, A. Tarullo 2, L. Laino 8, R. Sabatini 2, A. Abbinante 2, R. Cagiano 2

1 Department of Dental Sciences and Surgery, University of Bari, Bari, Italy

2 Department of Biomedical Sciences and Human Oncology, University of Bari, Bari, Italy

3 Maxillofacial Surgery Unit, Calabrodental Clinic, Crotone, Italy

4 Department of Basic Medical Sciences, University of Bari, Bari, Italy

5 Tecnologica Research Institute, Biomedical Unit, Crotone, Italy

6 Dental School, University of Milan, Milan, Italy

7 Dental School, University of Bari, Bari, Italy

8 Department of Odontology, 2nd University “Federico II” of Naples, Naples, Italy

 

 

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• Dentistry

OBJECTIVES: Aim of this work is to show the effectiveness of a protocol involving the use of platelet-rich plasma (PRP) as a grafting material in bone regeneration before dental implant rehabilitation.

MATERIALS AND METHODS: 127 patients, requiring maxillary sinus lift, were enrolled in a follow-up study plan, which established clinical and radiological examinations on the day after surgery and six months later. PRP, in combination with autogenous bone, anorganic bone material and organic bone substitutes, was used before implant-prosthetic rehabilitation.

RESULTS AND CONCLUSIONS: After implant placement, 63 patients, previously treated with PRP, reached a statistically significant improvement in implant-prosthetic rehabilitation, established by primary stability and radiographic integration criteria, in comparison with the other 64 patients receiving implant-prosthetic rehabilitation without PRP treatment.

Corresponding Author: Raffaele Cagiano, MD; e-mail: r.cagiano@farmacol.uniba.it

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