OBJECTIVE: To investigate whether leptin can regulate the apoptosis of nucleus pulposus cells by adjusting the autophagy of human degenerative nucleus pulposus cells and its possible molecular mechanism. PATIENTS AND METHODS: The human degenerative nucleus pulposus cells were extracted and cultured, then treated with leptin, leptin inhibitor and leptin neutralizing antibody; the expressions of light … Continue reading Leptin inhibits apoptosis of nucleus pulposus cells via promoting autophagy