OBJECTIVE: Sp1 is a member of super zinc finger structure family that participates in cancer cells’ apoptosis, proliferation, survival, and differentiation. This study detected the expressions of miR-375 and sp1 in colorectal cancer tissue and cells to analyze their impact on cell proliferation. PATIENTS AND METHODS: Colorectal cancer patients in our hospital were enrolled. HCT-116 … Continue reading The inhibitory effect of miR-375 targeting sp1 in colorectal cancer cell proliferation