The interplay of transcriptional and post-transcriptional regulation of migration of mesenchymal stem cells during early stages of bone fracture healing
C.-H. Dong, Y.-S. Deng, X.-J. Yang, J. Liu, R. Liu, F.-Y. Hou, S.-S. Li, P. Zhen Department of Sports Medicine, the Centre of Orthopedic Surgery of PLA, Lanzhou General Hospital, Gansu, China. zhenpingok@163.com
Bone fractures are a medical condition where the continuity of the bone is broken due to a fall or accident. The fracture may also be the result of medical conditions such as osteoporosis, cancers of bone or osteogenesis imperfect. During the bone fracture healing process, the mesenchymal stem cells (undifferentiated connective tissue cells) are recruited from local and systemic sources. The modulation of mesenchymal cell migration to the fractured site is the desired goal. Still, there are many processes that are still required to be studied and analyzed. We aimed to consolidate and review the available information on this topic.
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C.-H. Dong, Y.-S. Deng, X.-J. Yang, J. Liu, R. Liu, F.-Y. Hou, S.-S. Li, P. Zhen
The interplay of transcriptional and post-transcriptional regulation of migration of mesenchymal stem cells during early stages of bone fracture healing
Eur Rev Med Pharmacol Sci
Year: 2017
Vol. 21 - N. 24
Pages: 5542-5547
DOI: 10.26355/eurrev_201712_13990