Cancer stem cell markers in glioblastoma – an update
H.-S. Xu, X.-L. Qin, H.-L. Zong, X.-G. He, L. Cao Department of Neurosurgery, Affiliated Xuzhou Hospital of Southeast University, Xuzhou, Jiangsu Province, China. xhs51@126.com
The glioblastoma includes brain tumors, which are very aggressive in nature and are among the most common brain tumors in adults. Latest therapeutic avenues involve combination approach. However, the observed median survival is still no more than 15 months. Moreover, there is a scarcity of accurate pre-clinical model systems, which in turn resulted in limited treatment options for this disease. Cancer stem cells are attractive avenues in anticancer research against glioblastoma. Most of the recent studies are focused towards the identification of novel markers for cancer stem cells. The present review article is focused on two important markers in current research viz. Prominin-1 and NPM1 in glioblastoma.
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To cite this article
H.-S. Xu, X.-L. Qin, H.-L. Zong, X.-G. He, L. Cao
Cancer stem cell markers in glioblastoma – an update
Eur Rev Med Pharmacol Sci
Year: 2017
Vol. 21 - N. 14
Pages: 3207-3211