MiR-24 alleviates cardiomyocyte apoptosis after myocardial infarction via targeting BIM

OBJECTIVE: Ischemia hypoxia induces cardiomyocyte (CM) apoptosis in the process of acute myocardial infarction (AMI). It was showed that pro-apoptosis factor BIM participates in regulating tumor cell apoptosis under ischemia or hypoxia condition, while its role in CM apoptosis after AMI is still unclear. It was revealed that miR-24 expression was significantly reduced in myocardial … Continue reading MiR-24 alleviates cardiomyocyte apoptosis after myocardial infarction via targeting BIM