Imipenem-resistance in Serratia marcescens is mediated by plasmid expression of KPC-2

OBJECTIVE: Imipenem is a broad-spectrum carbapenem antibiotic with applications against severe bacterial infections. Here, we describe the identification of imipenem-resistant Serratia marcescens in our hospital and the role of plasmid-mediated KPC-2 expression in imipenem resistance. MATERIALS AND METHODS: We used the modified Hodge test to detect carbapenemase produced in imipenem-resistant strains. RESULTS: His resistance can be … Continue reading Imipenem-resistance in Serratia marcescens is mediated by plasmid expression of KPC-2