Eur Rev Med Pharmacol Sci 2015; 19 (2): 316-321

Irisin as an exercise-stimulated hormone binding crosstalk between organs

J. Liu

College of Health Science, Wuhan Sports University, Wuhan, China. liujun@wipe.edu.cn

Irisin is a newly discovered 112 amino acid residues’ glycosylated protein hormone that was firstly found up-regulated by exercise-induced peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1a) and then play an important role in circulation so as to target other organs. It conducts many downstream events including osteoblast differentiation, nerve cell and b-cell regeneration and so on. In clinical research, non-inflammation and inflammation related diseases correlated with basal level of irisin and they benefited from exercise-induced irisin endocrinology.

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To cite this article

J. Liu
Irisin as an exercise-stimulated hormone binding crosstalk between organs

Eur Rev Med Pharmacol Sci
Year: 2015
Vol. 19 - N. 2
Pages: 316-321

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