Eur Rev Med Pharmacol Sci 2009; 13 (5): 389-392

A neglected giant subcutaneous leiomyosarcoma of the shoulder: a case report

L. Palla, P. Gentile, C. Cannatà, P. Ascenzi, O. Buonomo*, V. Cervelli

Department of Plastic and Reconstructive Surgery; and *Department of Surgery, University of Study, “TorVergata”, Rome (Italy)


Superficial leiomyosarcoma is an exceeding uncommon malignant tumor, which can be located either cutaneous or subcutaneous tissues. It may occur anywhere in the body, but there is a predilection for the thighs. The distinction between cutaneous or subcutaneous, increased mass size (>5 cm) and depth are considered to have worst prognosis in terms of recurrence and metastasis.
We report a rare case of an 81-year-old woman, presented with a 20-cm leiomyosarcoma of the shoulder. The patient reported that the mass was completely asymptomatic and its growth was slow. A CT study showed a lesion closely apposed to the head of the humerus and revealed no a clear relationship with the surrounding muscles. There was no regional lymphadenopathy or the evidence of metastatic disease.
After tumor resection, a large skin and soft-tissue defect was remained and the repair was performed by myocutaneous rotational free flap of latissimus dorsi.
The conclusion of the histological analysis was: subcutaneous leiomyosarcoma pT2 – grade 1+ (NCI system).
The delayed diagnosis and the surgical treatment and giant size of soft tissue leiomyosarcoma may adversely affect the final result.

Corresponding Author: Palla Ludovico, MD; e-mail: ludovicopalla@hotmail.com

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To cite this article

L. Palla, P. Gentile, C. Cannatà, P. Ascenzi, O. Buonomo*, V. Cervelli
A neglected giant subcutaneous leiomyosarcoma of the shoulder: a case report

Eur Rev Med Pharmacol Sci
Year: 2009
Vol. 13 - N. 5
Pages: 389-392