Neonatal necrotizing enterocolitis: a focus on

M. Pellegrini, N. Lagrasta*, C. Garcìa Garcìa†, J. Campos Serna‡, E. Zicari**, G. Marzocca***

Scuola di Gastroenterologia, Dipartimento di Medicina Interna, Scienze Endocrino-Metaboliche e Biochimica
* Dipartimento di Pediatria, Ostetricia e Medicina della Riproduzione
** Istituto di Scienze Neurologiche
*** Cattedra di Clinica e Terapia Chirurgica, U.O. Chirurgia dell’Apparato Digerente, University of Siena (Italy)
† Servicio de Medicina Intensiva, Hospital General Universitario de Alicante (Spain)
‡ Facultad de Medicina Y Cirugia, Universidad Miguel Hernandez Alicante (Spain)

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• Gastroenterology

Abstract. – Necrotizing enterocolitis (NEC) is a multifactorial worldwide problem, representing the most frequent gastrointestinal emergency in neonates. Extremely common in preterm infants, it is also registered in fullterm low birth weight neonates. Despite extensive research, its etiopathogenesis is not completely understood and this neonatal disease remains associated with high morbidity and mortality rates. This review proposes an interdisciplinary focus on recent developments in NEC etiopathogenesis, diagnosis and management.

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