Changes of wound area and inflammatory factors in diabetic foot patients after comprehensive nursing of traditional Chinese medicine

L. Chen, W.-H. Zhong, Y.-D. Ma, Y.-J. Zhang, G.-C. Cai, H.-Q. Huang, F.-F. Lu, X.-D. Su

Department of Endocrinology, Department of Respiratory and Critical Care Medicine, Third People’s Hospital of Haikou, Haikou, Hainan, China. n3e0r9@sina.com

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• Diabetes

OBJECTIVE: The aim of this study is to analyze the application effect of traditional Chinese medicine (TCM) comprehensive nursing in diabetic foot patients.

PATIENTS AND METHODS: 230 patients with diabetic foot admitted to Third people’s Hospital of Haikou from January 2019 to April 2022 were classified as two groups, which consisted of a control group (n = 95) and an experimental group (n = 135). The control group took routine nursing intervention, while the experimental group took TCM comprehensive nursing intervention. The effect of intervention was compared by inflammatory factors (B-FGF, EGF, VEGF, and PDGF), wound area, self-rated anxiety scale (SAS), and self-rated depression scale (SDS).

RESULTS: After nursing, the levels of B-FGF, EGF, VEGF, and PDGF were higher in the experimental group (all p < 0.05). The total effective rate of diabetic foot recovery in the experimental group was 94.87% (74/78), higher than 87.67% (64/73) in the control group (p = 0.026). After nursing, the scores of SAS and SDS in the experimental group were lower than those in the control group (all p < 0.05).

CONCLUSIONS: The application of TCM comprehensive nursing in diabetic foot patients can greatly change the levels of B-FGF, EGF, VEGF, and PDGF in wound tissue, promote the healing of ulcer surface, improve patients’ anxiety and depression, and enhance the quality of life of patients.

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