An impressive case of alopecia universalis after COVID-19 vaccination: a coincidental finding or a consequence?

L. Peterle, L. Macca, F. Li Pomi, F. Vaccaro, F. Borgia, M. Vaccaro

Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy. mario.vaccaro@unime.it

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• Dermatology
• Immunology
• Infectious Diseases

BACKGROUND: Several cutaneous manifestations in patients undergoing COVID-19 vaccination have been described in literature.

CASE REPORT: Herein, we present a case of alopecia universalis that occurred after the first and second dose of Comirnaty vaccine. A bibliographic search was conducted and a total of 14 studies concerning the association were reviewed.

CONCLUSIONS: Given the autoimmune pathogenesis of the disease, we discussed the potential role of SARS-CoV-2 infection and vaccination as a trigger for the development of hair loss. Physicians should be aware of SARS-CoV-2 vaccine-related hair loss and properly treat this undesirable effect.

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