Tolerability of doxofylline in the maintenance therapy of pediatric patients with bronchial asthma

G.F. Bagnato

Dipartimento di Medicina Interna e Terapia Medica, Messina University (Italia)

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• Respiratory Medicine

A retrospective open study was performed to ascertain the tolerability of doxofylline in pediatric patients with bronchial asthma or airway obstruction complicating acute bronchitis. The study population included 806 patients aged between 3 and 16 years. Doxofylline (200 mg sachets) was administered at daily doses ranging from 100 to 400 mg. The percentage of patients reporting side effects was 11%. The percent of patients reporting moderate side effect was 5%, the others being mild. The percent of patients reporting adverse event very likely due to doxofylline was 6%. The percent of patient drop-outs related to side effects was 5%.

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