Eur Rev Med Pharmacol Sci 2004; 8 (1): 11-18

Diagnosis of liver fibrosis

A. Di Sario, G. Feliciangeli, E. Bendia, A. Benedetti

Department of Gastroenterology, Università Politecnica delle Marche, Ancona – (Italy)


Hepatic fibrosis and cirrhosis represent the main consequence of chronic liver diseases of different origin. Therefore, the clinical assessment of disease severity is a must in the management of patients with chronic liver damage. Although liver biopsy may be associated with sampling error, interobserver variability and potential complications, it still remains the gold standard for establishing the severity of hepatic necroinflammation and fibrosis. In the last years, several non-invasive tests for the assessment of disease activity and stage have been proposed. However, at present all these tests are not totally accurate and reliable and need further evaluation.

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To cite this article

A. Di Sario, G. Feliciangeli, E. Bendia, A. Benedetti
Diagnosis of liver fibrosis

Eur Rev Med Pharmacol Sci
Year: 2004
Vol. 8 - N. 1
Pages: 11-18